BGC > Product Search > ICA 069673 | 582323-16-8

Description :
ICA-069673 is an orally active, potent and selective KCNQ2/Q3 potassium channel activator (IC50= 0.69 μM) with 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5 (EC50s = 14.3 μM).

• Molecular Weight :269.63
• Boiling Point :358.9±37.0 ℃ at 760 Torr

Molecular Formula :
C11H6ClF2N3O
Canonical SMILES :
C1=CC(=C(C=C1C(=O)NC2=CN=C(N=C2)Cl)F)F
InChI :
InChI=1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
InChIKey :
IIBSHMFXVWTQSJ-UHFFFAOYSA-N
Solubility :
DMSO: ≥ 34 mg/mL
Storage : Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms :
ICA 069673; ICA069673

More details are to be found here

Description :
ICA-069673 is an orally active, potent and selective KCNQ2/Q3 potassium channel activator (IC50= 0.69 μM) with 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5 (EC50s = 14.3 μM).

• Molecular Weight :269.63
• Boiling Point :358.9±37.0 ℃ at 760 Torr

Molecular Formula :
C11H6ClF2N3O
Canonical SMILES :
C1=CC(=C(C=C1C(=O)NC2=CN=C(N=C2)Cl)F)F
InChI :
InChI=1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
InChIKey :
IIBSHMFXVWTQSJ-UHFFFAOYSA-N
Solubility :
DMSO: ≥ 34 mg/mL
Storage : Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms :
ICA 069673; ICA069673

More details are to be found here